Details for gene set KEGG_SYSTEMIC_LUPUS

Table: GSEA Results Summary

Dataset	RNR_GSEA_DESEQ2_FC
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_neg
GeneSet	KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS
Enrichment Score (ES)	-0.18730167
Normalized Enrichment Score (NES)	-2.503118
Nominal p-value	0.0
FDR q-value	0.00182227
FWER p-Value	0.012

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	HIST1H3F	258	1.316	-0.0056	No
2	HIST1H2BI	314	1.169	-0.0002	No
3	HIST1H2AI	333	1.136	0.0071	No
4	HIST1H2BL	463	0.953	0.0085	No
5	HIST2H4A	866	0.582	-0.0049	No
6	HIST1H2AL	936	0.555	-0.0003	No
7	H3F3C	1023	0.506	0.0034	No
8	HIST2H2AA4	1161	0.449	0.0043	No
9	HLA-DQA2	1217	0.435	0.0097	No
10	HIST1H4K	1302	0.404	0.0135	No
11	HIST1H4B	1461	0.353	0.0133	No
12	HIST1H3I	1465	0.352	0.0215	No
13	CD28	1505	0.348	0.0277	No
14	HIST1H2AB	1575	0.334	0.0323	No
15	C8G	1578	0.333	0.0405	No
16	IFNG	1662	0.317	0.0444	No
17	TNF	1751	0.302	0.0479	No
18	C7	1762	0.300	0.0557	No
19	C2	1848	0.286	0.0595	No
20	CD80	1856	0.284	0.0674	No
21	HIST1H2BE	1886	0.279	0.0742	No
22	FCGR2B	1919	0.272	0.0808	No
23	HIST4H4	2045	0.256	0.0824	No
24	GRIN2A	2109	0.250	0.0873	No
25	HIST1H4J	2275	0.231	0.0867	No
26	ACTN2	2341	0.224	0.0916	No
27	CD86	3015	0.172	0.0635	No
28	HIST1H3H	3148	0.163	0.0647	No
29	C1QB	3169	0.161	0.0720	No
30	C1QC	3422	0.149	0.0667	No
31	HIST1H3E	3453	0.148	0.0734	No
32	HIST1H4I	3978	0.123	0.0534	No
33	C1QA	4253	0.113	0.0470	No
34	HIST2H2AC	4257	0.113	0.0551	No
35	TROVE2	4575	0.102	0.0464	No
36	C9	4687	0.098	0.0487	No
37	CTSG	4891	0.092	0.0461	No
38	H2AFJ	5750	0.068	0.0080	No
39	C5	5772	0.068	0.0152	No
40	HIST2H2BE	5790	0.067	0.0227	No
41	ACTN4	6106	0.060	0.0140	No
42	H2AFY	7020	0.039	-0.0270	No
43	IL10	7126	0.037	-0.0244	No
44	H2AFV	7381	0.031	-0.0297	No
45	HIST1H2AK	7464	0.030	-0.0258	No
46	SNRPD3	7566	0.027	-0.0230	No
47	HIST1H2BO	9784	-0.017	-0.1344	No
48	HIST2H2AA3	9836	-0.018	-0.1288	No
49	H3F3B	10020	-0.021	-0.1304	No
50	H2AFZ	10077	-0.022	-0.1251	No
51	SSB	10503	-0.030	-0.1397	No
52	HIST2H2AB	10845	-0.038	-0.1498	No
53	C6	10972	-0.041	-0.1483	No
54	HIST1H2BG	11083	-0.044	-0.1459	No
55	HLA-DMA	11724	-0.059	-0.1721	No
56	HLA-DPA1	11815	-0.061	-0.1686	No
57	H2AFY2	12032	-0.066	-0.1720	No
58	HLA-DMB	12266	-0.071	-0.1762	No
59	FCGR2A	12338	-0.073	-0.1717	No
60	H2AFX	12424	-0.075	-0.1680	No
61	H3F3A	12523	-0.078	-0.1649	No
62	SNRPD1	12582	-0.080	-0.1597	No
63	HIST2H2BF	12877	-0.089	-0.1673	No
64	HIST1H2AM	12906	-0.089	-0.1605	No
65	HIST1H2BH	13167	-0.098	-0.1662	No
66	HIST1H3A	13249	-0.100	-0.1622	No
67	SNRPB	13400	-0.105	-0.1620	No
68	TRIM21	13421	-0.106	-0.1547	No
69	HIST1H2BD	13895	-0.123	-0.1720	No
70	CD40	14170	-0.137	-0.1784	No
71	HIST1H2BK	14331	-0.146	-0.1787	No
72	HIST1H2BJ	14357	-0.147	-0.1718	No
73	ACTN1	14470	-0.152	-0.1695	No
74	HIST3H2A	14801	-0.171	-0.1790	Yes
75	HIST1H2BN	14817	-0.172	-0.1714	Yes
76	HLA-DRA	14894	-0.178	-0.1672	Yes
77	C1S	14961	-0.182	-0.1624	Yes
78	HIST3H2BB	15018	-0.187	-0.1571	Yes
79	HIST1H4H	15214	-0.202	-0.1593	Yes
80	HIST1H4D	15239	-0.204	-0.1523	Yes
81	HIST1H3G	15319	-0.211	-0.1482	Yes
82	HLA-DPB1	15325	-0.211	-0.1402	Yes
83	C1R	15344	-0.213	-0.1328	Yes
84	HIST1H2AC	15363	-0.215	-0.1255	Yes
85	HLA-DOA	15422	-0.220	-0.1203	Yes
86	CD40LG	15950	-0.282	-0.1404	Yes
87	HIST1H3D	15979	-0.285	-0.1336	Yes
88	FCGR3A	15990	-0.286	-0.1258	Yes
89	HIST1H2AG	15998	-0.287	-0.1178	Yes
90	C3	16057	-0.294	-0.1126	Yes
91	HIST1H2BC	16117	-0.303	-0.1075	Yes
92	HIST1H2AE	16297	-0.334	-0.1088	Yes
93	FCGR1A	16322	-0.338	-0.1018	Yes
94	H2BFM	16338	-0.340	-0.0943	Yes
95	H2AFB1	16381	-0.349	-0.0882	Yes
96	HIST1H4A	16399	-0.354	-0.0808	Yes
97	HIST1H4E	16414	-0.357	-0.0732	Yes
98	FCGR3B	16570	-0.393	-0.0732	Yes
99	HIST2H3D	16790	-0.450	-0.0767	Yes
100	HIST1H2AJ	17007	-0.505	-0.0801	Yes
101	C4A	17051	-0.518	-0.0741	Yes
102	HIST3H3	17089	-0.532	-0.0677	Yes
103	HLA-DRB1	17183	-0.571	-0.0644	Yes
104	C4B	17298	-0.628	-0.0622	Yes
105	HIST1H3J	17420	-0.690	-0.0604	Yes
106	HLA-DRB5	17494	-0.732	-0.0561	Yes
107	HLA-DOB	17586	-0.794	-0.0526	Yes
108	HIST1H3C	17675	-0.864	-0.0491	Yes
109	HIST2H4B	17682	-0.871	-0.0410	Yes
110	HIST1H2BF	17759	-0.929	-0.0368	Yes
111	ELANE	17814	-0.966	-0.0314	Yes
112	HLA-DQA1	17848	-0.994	-0.0249	Yes
113	HIST1H2BB	17900	-1.037	-0.0193	Yes
114	HIST1H2BM	18044	-1.179	-0.0187	Yes
115	GRIN2B	18050	-1.185	-0.0106	Yes
116	C8A	18115	-1.261	-0.0057	Yes
117	HIST1H4C	18155	-1.345	0.0005	Yes
118	HIST1H4F	18197	-1.443	0.0066	Yes
119	HIST1H3B	18269	-1.518	0.0111	Yes
120	HLA-DQB1	18283	-1.547	0.0187	Yes